The intake of the oral drugs gives you the cure from impotence within an hour. These drugs are basically the derivatives of phosphodiesterase inhibitors that work in the body by retarding the activity of the phosphodiesterase 5 (PDE-5) enzyme. The first impotence medication discovery by the Pfizer was the real breakthrough in the medicine world. It is the by-mistake discovery done by Pfizer as it was checking the Sildenafil for Angina pectoris, but during the clinical trials this medication showed effects on erectile mechanism of men. The men who took it got the stiff state of the male reproductive organ and the same condition stayed for about 4 hours. Thus, it gave scientists an idea about the hidden use of Sildenafil.

Oral drug cure impotency in men by promoting the blood flow to the male reproductive system. The efficient amount of the blood is required for the male reproductive organ to attain the stiff state during the love-making activity. The insufficient amount of the blood flow is the main reason behind the occurrence of the impotence. The enzyme PDE-5 is responsible for cutting off the necessary blood flow. The oral drug improves the blood flow by inhibiting the activity of the enzyme PDE-5.

Intake of these medicines is recommended to be done only after you take a prescription from the doctor. The most famous oral drugs used to cure impotency are Viagra, Cialis, and Levitra. Any of these medications you can use to resolve the issue of impotency. Three of these medicines are being approved by the FDA for the treatment of the impotency in men, so don’t worry about their safety and efficacy.

It was after the discovery of the Viagra that another company started finding the potential of the other phosphodiesterase inhibitors in the treatment of the impotency. This gave rise to the two new medicines, Cialis and Levitra. The chemical constituent of the Cialis is Tadalafil and that of Levitra is Vardenafil online pharmacy. Both these medicines are perfectly effective against the impotence in men like that of Viagra.

The effect of Viagra is seen in about 1 hour to show effect, Cialis takes 30 minutes, and Levitra takes 40 minutes to show the effect. The effect of Viagra and Levitra stays for about 4 to 6 hours and that of Cialis stays for about 24 to 36 hours. Thence Cialis is termed as the Weekend pill due to long-lasting effect. Whatever may be the reason for the impotency these medicines will show you the effect. Age is no bar for working of these oral drugs against the impotence. But, which medicines out of these oral drugs should be taken must be decided only after taking your family physician’s advice.

The intake of the oral drugs augments the production of the enzyme cyclic guanoyl monophosphatase. This enzyme is needed in the male reproductive system in the enough amounts as this enzyme regulates the blood flow to the male reproductive organ and enables the impotent men to attain the stiff state during the love-making act. The nitric oxide deposition in the male reproductive organ is must for the man to attain stiff state, which is improved by the intake of the oral medicines. Only one pill of the oral drug is adequate to resolve impotency problem.

Take this pill with the water as it will help the active constituent of the medicine to dissolve easily and reach the blood stream as soon as possible. Thus it enables the impotent men to get it strong and hold it too for the long time while making love with the partner.